You must be logged on as the Administrator on that system.
Steps to make your drive Write Protected:
1. Open Registry Editor by typing regedit in Run dialog.
2. Navigate to the key HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\
3. Find a sub key inside it named “StorageDevicePolicies”. If it does not exist there then we need to make it. Right click on “Control” key -> New -> Key. Name it “StorageDevicePolicies” without quotes.
4. Now right click on this newly created key and then click New -> DWORD value and name it as “WriteProtect”.
5. Modify this key and give it a value 1.
and reboot your system.Now no more data can be transferred to the drive but to start using the drive again just give the “WriteProtect” key a value of 0 instead of 1 and restart the PC.